Purdue University Graduate School
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CAMPYLOBACTER JEJUNI PERIPLASMIC NITRATE REDUCTASE NAPA AS A MEDIUM FOR ELUCIDATING MOLYBDENUM COFACTOR REACTIVITY

thesis
posted on 2025-06-02, 12:25 authored by Mikayla Christine MetzgerMikayla Christine Metzger

This research contributed to understanding the nitrate reductase NapA in the prevalent pathogen Campylobacter jejuni. Cj NapA catalyzes the reduction of nitrate to nitrite within the human gastrointestinal tract for survival.

Funding

Mechanism of Substrate Transformations by the Complex Iron Sulfur Molybdoenzyme (CISM) Family

Directorate for Mathematical & Physical Sciences

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Investigation of Molybdenum Cofactor through Chemical, Biochemical and Biophysical Studies

National Institute of General Medical Sciences

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History

Degree Type

  • Doctor of Philosophy

Department

  • Chemistry

Campus location

  • Indianapolis

Advisor/Supervisor/Committee Chair

Partha Basu

Additional Committee Member 2

Brenda Blacklock

Additional Committee Member 3

Ian Webb

Additional Committee Member 4

Jingzhi Pu

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