This research evaluates Kidney Health Initiative's (KHI) four kidney replacement therapy (KRT) technology priority groups in the roadmap:
1) Literature review of technology citations for each of the four KHI priority groups for safety and efficacy data with a patient centered focus. Additionally, the incorporation and integration of KHI minimum technical design criteria in six areas into the development process.
2) Clinical PICO analysis of the critical clinical outcomes that the discovery and innovation from the specific technology priority group addresses
3) Critical evaluation of KRT technologies on patients with ESKD by expert clinicians and scientists in KRT through Delphi method with targeted questionnaires