DYNAMIC CONTROL OF HYDROGEL PROPERTIES VIA ENZYMATIC REACTIONS

Moore, Dustin Michael

doi:10.25394/PGS.8025614.v1

Moore_MS-Thesis_2019.pdf (20.74 MB)

DYNAMIC CONTROL OF HYDROGEL PROPERTIES VIA ENZYMATIC REACTIONS

thesis

posted on 2019-06-10, 20:37 authored by Dustin Michael MooreDustin Michael Moore

Two Systems were designed. The first permits tunable on-demand softening of a hydrogel network. The second permits reversible on demand ligand exchange within a hydrogel network. Both means were shown to be cytocompatible and their uses demonstrated in cell culture of mesenchymal stem cells and 3T3 fibroblast cells.

History

Degree Type

Master of Science in Biomedical Engineering

Department

Biomedical Engineering

Campus location

Indianapolis

Advisor/Supervisor/Committee Chair

Dr. Chien-Chi Lin

Advisor/Supervisor/Committee co-chair

Dr. Dong Xie

Additional Committee Member 2

Dr. Jiliang Li

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Keywords

Tissue engineering hydrogel softening Sortase A Ligand Exchange Mesenchymal Stem Cells 3T3 Fibroblast Cells Biomechanical Engineering

Licence

CC BY 4.0

DYNAMIC CONTROL OF HYDROGEL PROPERTIES VIA ENZYMATIC REACTIONS

History

Degree Type

Department

Campus location

Advisor/Supervisor/Committee Chair

Advisor/Supervisor/Committee co-chair

Additional Committee Member 2

Usage metrics

Categories

Keywords

Licence

Exports