Purdue University Graduate School
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Alvarado MS 2022.pdf (1.05 MB)

Does consumption of a Western Diet during early development exacerbate hippocampal microgliosis after Pilocarpine-induced Status Epilepticus?

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posted on 2022-04-27, 13:32 authored by Cynthia D AlvaradoCynthia D Alvarado

The goal of this study is to use a rat model of acquired temporal lobe epilepsy, pilocarpine-induced status epilepticus (SE), to test the hypothesis that WD exacerbates the inflammatory consequences of SE in hippocampus of male rats. Testing this hypothesis in animals consuming WD from early in life may provide insight into how a modifiable environmental factor could influence the development of seizure disorders. 

History

Degree Type

  • Master of Science

Department

  • Psychological Sciences

Campus location

  • West Lafayette

Advisor/Supervisor/Committee Chair

Susan E. Swithers

Additional Committee Member 2

Jason R. Cannon

Additional Committee Member 3

Kimberly P. Kinzig

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