Purdue University Graduate School
AShell Dissertation Purdue 2022.pdf (1.87 MB)

Effect of Depression Treatment on Somatic Depressive Symptoms and Cardiometabolic Biomarkers among People without Diabetes

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posted on 2022-09-09, 14:25 authored by Aubrey Lynn ShellAubrey Lynn Shell

Examining the effect of a modernized collaborative care intervention for depression consisting of both behavioral and pharmacologic treatments on 12-month change in individual somatic depressive symptoms (hyperphagia, poor appetite, hypersomnia, and disturbed sleep) and 12-month change in

cardiometabolic biomarkers (HOMA-IR, BMI, hsCRP, leptin, and ghrelin). Further examining whether 12-month change in individual somatic depressive symptoms mediates the eIMPACT intervention’s effect on 12-month change in cardiometabolic biomarkers.


Degree Type

  • Doctor of Philosophy


  • Psychological Sciences

Campus location

  • Indianapolis

Advisor/Supervisor/Committee Chair

Jesse C. Stewart

Additional Committee Member 2

Adam T. Hirsh

Additional Committee Member 3

Melissa A. Cyders

Additional Committee Member 4

Robert V. Considine