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Effects of Formulation and Manufacturing Conditions on Protein Structure and Physical Stability
thesisposted on 06.11.2019, 21:05 by Nathan E Wilson
This work focuses on the effects of formulation and manufacturing as it effects protein structure and physical stability. Using common physical characterization techniques, X-ray photoelectron spectroscopy, and solid-state hydrogen/deuterium exchange with mass spectrometry, correlations are identified between these results and accelerated stability studies.