Effects of Formulation and Manufacturing Conditions on Protein Structure and Physical Stability
thesisposted on 2019-11-06, 21:05 authored by Nathan E WilsonNathan E Wilson
This work focuses on the effects of formulation and manufacturing as it effects protein structure and physical stability. Using common physical characterization techniques, X-ray photoelectron spectroscopy, and solid-state hydrogen/deuterium exchange with mass spectrometry, correlations are identified between these results and accelerated stability studies.
- Doctor of Philosophy
- Industrial and Physical Pharmacy
- West Lafayette