Bohyun Ro_Thesis.pdf

Reason: Some of the data and contents have not been published yet and plan to be published in the future.

27

day(s)

until file(s) become available

IMPACT OF HEAT THERAPY ON SKELETAL MUSCLE FUNCTION IN A MODEL OF DUCHENNE MUSCULAR DYSTROPHY

thesis
posted on 28.07.2021, 05:41 by Bohyun RoBohyun Ro
Current study demonstrated the impact of heat therapy on skeletal muscle function in a model of Duchenne muscular dystrophy (DMD). The aim of this study was to: (1) examine the impact of treatment temperature on the skeletal muscle adaptation in DBA/2J mice; and (2) determine the impact of repeated HT for 3 consecutive weeks on body composition and skeletal muscle function in D2.mdx, a model of DMD. From study 1, we revealed that HT at 39℃ for 3 weeks significantly promoted relative muscle mass of both EDL and soleus muscle in DBA/2J mice. However, from study 2, HT at 39℃ for 3 weeks does not improve muscle function or increase muscle mass in a mouse model of DMD.

Funding

Indiana CTSI

History

Degree Type

Master of Science

Department

Health and Kinesiology

Campus location

West Lafayette

Advisor/Supervisor/Committee Chair

Bruno T. Roseguini

Additional Committee Member 2

Timothy P. Gavin

Additional Committee Member 3

Daniel M. Hirai

Additional Committee Member 4

Shihuan Kuang