Purdue University Graduate School
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Identifying High Acute Care Users Among Bipolar and Schizophrenia Patients

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posted on 2024-01-03, 15:10 authored by Shuo LiShuo Li

The electronic health record (EHR) documents the patient’s medical history, with information such as demographics, diagnostic history, procedures, laboratory tests, and observations made by healthcare providers. This source of information can help support preventive health care and management. The present thesis explores the potential for EHR-driven models to predict acute care utilization (ACU) which is defined as visits to an emergency department (ED) or inpatient hospitalization (IH). ACU care is often associated with significant costs compared to outpatient visits. Identifying patients at risk can improve the quality of care for patients and can reduce the need for these services making healthcare organizations more cost-effective. This is important for vulnerable patients including those suffering from schizophrenia and bipolar disorders. This study compares the ability of the MedBERT architecture, the MedBERT+ architecture and standard machine learning models to identify at risk patients. MedBERT is a deep learning language model which was trained on diagnosis codes to predict the patient’s at risk for certain disease conditions. MedBERT+, the architecture introduced in this study is also trained on diagnosis codes. However, it adds socio-demographic embeddings and targets a different outcome, namely ACU. MedBERT+ outperformed the original architecture, MedBERT, as well as XGB achieving an AUC of 0.71 for both bipolar and schizophrenia patients when predicting ED visits and an AUC of 0.72 for bipolar patients when predicting IH visits. For schizophrenia patients, the IH predictive model had an AUC of 0.66 requiring further improvements. One potential direction for future improvement is the encoding of the demographic variables. Preliminary results indicate that an appropriate encoding of the age of the patient increased the AUC of Bipolar ED models to up to 0.78.


George Katz | Merck Sharp & Dohme Research Laboratories - Estados Unidos

São Paulo Research Foundation

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Degree Type

  • Master of Science


  • Computer Science

Campus location

  • Indianapolis

Advisor/Supervisor/Committee Chair

Shiaofen Fang

Advisor/Supervisor/Committee co-chair

Zina Ben-Miled

Additional Committee Member 2

Jiang Yu Zheng

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