Purdue University Graduate School
Browse
Philip Kauffmann dissertation (FINAL).pdf (10.21 MB)

Multibarrel Electrodes for Multipurpose Electroanalysis

Download (10.21 MB)
thesis
posted on 2024-06-20, 12:30 authored by Philip James KauffmannPhilip James Kauffmann

Small volume entities, such as aerosols, microdroplets, and cells, hold many truths of nature that are only recently being discovered. For example, researchers are finding that the reaction rates of certain entities are orders of magnitude larger in microdroplets than in bulk solutions, and that this effect scales with droplet size. Thus, the heterogeneity within populations of each of these environments require analysis at the single entity level. In order to probe these systems, new measurement tools must be developed. To this end, electrochemistry offers a sensitive, rapid, and affordable platform with which to make these kinds of measurements. In addition, electrochemistry can be adapted to detect a vast array of analytes, from environmental contaminants like per- and polyfluoroalkyl substances (PFAS, i.e. “Forever Chemicals”), to heavy metals like lead, to energetics like 2,4,6-trinitrotoluene (TNT). Aerosol sampling can be performed using a modified technique called Particle-Into-Liquid Sampling for Nanoliter Electrochemical Reactions (PILSNER). Building upon this, entire electrochemical cells can be miniaturized into a single probe (10s-100s of micrometers in diameter) for single aerosol detection, as well as single cell and microdroplet electroanalysis. Using fundamental principles and mathematical solutions, these probes can also be used to investigate temperature change and ice nucleation in microdroplets. This dissertation demonstrates the utility of electrochemistry to probe a wide range of small volume entities.

History

Degree Type

  • Doctor of Philosophy

Department

  • Chemistry

Campus location

  • West Lafayette

Advisor/Supervisor/Committee Chair

Dr. Jeffrey Dick

Additional Committee Member 2

Dr. Alexander Laskin

Additional Committee Member 3

Dr. Chi Zhang

Additional Committee Member 4

Dr. Muhammad Alam

Usage metrics

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC