Purdue University Graduate School
Lory dissertation final.pdf (1.17 MB)

Restricted and Repetitive Behavior in Autism Spectrum Disorder: An Examination of Functional Subtypes and Neurophysiological Features

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posted on 2021-08-27, 17:36 authored by Catharine LoryCatharine Lory

Restricted and repetitive behavior (RRB) is a core feature of autism spectrum disorder (ASD). Research suggests that the severity of RRB may be influenced by both environmental variables (e.g., absence of sensory stimulation input) and neurophysiological activity within the body (e.g., atypical regulatory capacity of the autonomic nervous system). Substantial research efforts have been devoted to the assessment of factors that influence the occurrence of RRB in individuals with ASD, which have led to the development of assessment methodologies, such as functional analysis, to identify specific contexts in which RRB occurs, and measures of heart rate variability (HRV) to index the level of neurophysiological activity for individuals with ASD.

However, despite the increasing consensus that the assessment and treatment of RRB require a more comprehensive approach due to the complexity and heterogeneity of the neurodevelopmental disorder, there exists a paucity in research that addresses both the functional behavioral and neurophysiological dimensions of RRB. This study aimed to address this gap by (a) designing and evaluating the effects of an integrated function-based assessment on identification of the functional subtypes of RRB and (b) examining the relationship between RRB and HRV as an indicator of neurophysiological functioning. The study included six participants, ages four to seven, with ASD. A single-case alternating treatments design, with two conditions simulating low- and high-stimulation environments, was used for the assessment of functional subtypes within each participant. Dependent variables included the duration of RRB and HRV. RRB was measured using MOOSES, a multi-option observation system for experimental studies. HRV was measured using wearable technology that collects blood volume pulse. Visual analysis of time series data as well as nonparametric analyses of the dependent variables were conducted to determine the functional subtypes of RRB and the association between HRV and RRB across participants.

Study results suggest that (a) the integrated assessment is effective in identifying specific functional subtypes of RRB and (b) HRV is positively correlated with the rate of RRB. The findings of this study offer new insights on the understanding of how underlying environmental and neurophysiological mechanisms may influence the occurrence of RRB in ASD. Furthermore, the study provides an integrated assessment model that can be feasibly implemented in applied settings.


Degree Type

  • Doctor of Philosophy


  • Educational Studies

Campus location

  • West Lafayette

Advisor/Supervisor/Committee Chair

Mandy Rispoli

Additional Committee Member 2

Brandon Keehn

Additional Committee Member 3

Rose A. Mason

Additional Committee Member 4

Benjamin A. Mason

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