Ye-Cheng Wang's thesis

Reason: Three projects are in manuscript preparation or under reviewed process.

2

year(s)

9

month(s)

27

day(s)

until file(s) become available

TOTAL SYNTHESES OF BERGAMOTANE SESQUITERPENES AND LYCOPODIUM ALKALOIDS AND COMPUTATIONAL STUDY TOWARD DIAMINATION OF ALLENES AND [2+2] SELECTIVITY

thesis
posted on 27.10.2022, 12:25 authored by Ye-Cheng Wang

Total synthesis of massarinolin A, purpurlides B, D, E, 2,3-deoxypurpurolide C, phleghenrines A and B were finished. A halogen bond promoted michael addiation was discovered during mechanism study toward diamination of allenes. Computational chemsitry study conducted toward the selectivity of 2+2 reaction supported the proposed key reaction during total synthesis of gibberellic acid 18.

Funding

NIH GM128570

NIH CA023168

NSF 2102022

NSF 1625543

History

Degree Type

Doctor of Philosophy

Department

Chemistry

Campus location

West Lafayette

Advisor/Supervisor/Committee Chair

Mingji Dai

Advisor/Supervisor/Committee co-chair

Christopher Uyeda

Additional Committee Member 2

Abram J. Axelrod

Additional Committee Member 3

Elizabeth I. Parkinson